منابع مشابه
Molecular Pathology of Lung Cancer: Current Status and Future Directions
The rapid development of targeted therapies has enormously changed the clinical management of lung cancer patients over the past decade; therefore, molecular testing, such as epidermal growth factor receptor (EGFR) gene mutations or anaplastic lymphoma kinase (ALK) gene rearrangements, is now routinely used to predict the therapeutic responses in lung cancer patients. Moreover, as technology an...
متن کاملPathology of lung cancer.
Microscopic examination of stained smears and tissue sections remains the standard method for definitive diagnosis and classification of lung cancer. However, the morphology of lung cancer is complex, and consensus classifications such as those prepared by a panel World Health Organization (WHO) are required for the sake of consistency and clinical relevance. In the most recent (1999) WHO class...
متن کاملPathology of lung cancer.
This article reviews current concepts in pathologic classification of lung cancer based on 1999 World Health Organization (WHO)/International Association for the Study of Lung Cancer (IASLC) classification. Preinvasive lesions including squamous dysplasia/carcinoma in situ, atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia are discussed in additio...
متن کاملDiagnostic Surgical Pathology in Lung Cancer
4.1.1. In individuals with parenchymal-based tu mors, distinguishing between small cell Background: This article provides evidence-based background and recommendations for the development of American College of Chest Physicians guidelines for the diagnosis and management of lung cancer. Specifi c population, intervention, comparison, and outcome questions were addressed to arrive at consensus r...
متن کامل[Molecular pathology of colorectal cancer].
The identification of several types of familial colorectal cancer has led to the discovery of some of the genes involved in these diseases. It was subsequently shown that somatic mutations of these genes (APC, mismatch repair genes, TP53) also occur in sporadic colorectal cancer. Gradually, this molecular information is being incorporated into the standard histopathological analysis of colorect...
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ژورنال
عنوان ژورنال: International Journal of Medical Reviews and Case Reports
سال: 2019
ISSN: 2534-9821
DOI: 10.5455/ijmrcr.molecular-pathology-in-lung-cancer